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22 J.L. Inf. & Sci. 98 (2012-2013)
Managing Intellectual Property to Promote Pre-Competitive Research: The Mouse as a Model for Constructing a Robust Research Commons

handle is hein.journals/jlinfos22 and id is 110 raw text is: Managing Intellectual Property to Promote Pre-
Competitive Research: The Mouse as a Model for
Constructing a Robust Research Commons
1   Introduction
New models for research and innovation are emerging in the life sciences,
with emphasis placed on collaboration and partnership between a variety of
stakeholders, including academia, government, industry and non-
governmental organizations.' At the same time, a deluge of biological data is
being generated around the world, primarily due to the advent of high-
throughput technologies such as next-generation sequencing, RNAseq, and
array based gene expression analysis.' More recently population genetics and
systematic phenotype analysis of model organisms' such as the mouse and
zebrafish have begun to generate large volumes of complex and multi-layered
data, while a similar explosion is occurring in the availability of bioresources
fundamental to biomedical research, such as mutant mouse strains. The latter
is due in part to a coordinated high-throughput community project, the
International Knockout Mouse Consortium (IKMC),' which is generating and
Tania Bubela has a PhD (Biology, University of Sydney, Australia) and JD
(University of Alberta, Canada) and is an Associate Professor in the Department of
Public Health Sciences, School of Public Health, University of Alberta, Canada; Dr
Paul Schofield has a DPhil in Biochemistry from the University of Oxford, is
Reader in Biomedical Informatics in the Department of Physiology Development
and Neuroscience, University of Cambridge, United Kingdom; Dr Cami Ryan is
with the Department of Bioresource Policy, Business and Economics College of
Agriculture and Bioresources, University of Saskatchewan, Canada; Rhiannon
Adams is an intellectual property lawyer with Parlee McLaws LLP, Edmonton,
Alberta, Canada; and David Einhorn is house counsel for The Jackson Laboratory,
Bar Harbor, Maine, USA.
Tania Bubela, Garret A FitzGerald and E Richard Gold, Recalibrating Intellectual
Property Rights to Enhance Translational Research Collaborations (2012) 4 Science
Translational Medicine 122cm3.
2  Julian  Parkhill, Ewan  Birney  and Paul Kersey, Genomic Information
Infrastructure after the Deluge (2010) 11 Genome Biology 402.
3  Steve D M Brown and Mark W Moore, Towards an Encyclopaedia of Mammalian
Gene Function: The International Mouse Phenotyping Consortium (2012) 5
Disease Models & Mechanisms 289; Zebrafish Mutation Project, Wellcome Trust Sanger
Institute (2012) <http:/ /www.sanger.ac.uk/Projects/Djrerio/ zmp />.
4  Francis S Collins, Janet Rossant and Wolfgang Wurst, A Mouse for all Reasons
(2007) 128 Cell 9; William C Skarnes et al, A Conditional Knockout Resource for
the Genome-Wide Study of Mouse Gene Function (2011) 474 Nature 337.


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