About | HeinOnline Law Journal Library | HeinOnline Law Journal Library | HeinOnline

34 Issues L. & Med. 15 (2019)
The Perinatal Revolution

handle is hein.journals/ilmed34 and id is 19 raw text is: 

        The Perinatal Revolution

  Colleen Malloy, M.D.,* Monique Chireau Wubbenhorst, M.D., MPH,**
                      and Tara Sander Lee, Ph.D.***

ABSTRACT: The Perinatal Revolution is an exciting and rapidly developing
field of medicine that aims to treat and possibly cure disease in the prena-
tal period, and thereby to improve health across the lifespan of the child.
Here we describe an overview of the perinatal field, with specific emphasis
on current therapies and interventions for specific fetal problems, such as
myelomeningocele and congenital diaphragmatic hernia. Advances in peri-
natal medicine have resulted in increased survival rates and improvements
in morbidity and mortality for premature neonates. Novel innovations in
screening and genetic diagnosis, as well as future prospects in cell-based
therapies, tissue engineering, gene therapy, and artificial womb are sig-
nificantly expanding the field and are discussed. Ethical, regulatory and
policy concerns closely linked to clinical practice and public awareness are
also highlighted as the Perinatal Revolution continues to unfold through
research, genetic, medical and surgical advances.

     Perhaps the final frontier of medicine is fetal diagnosis and therapy With advance-
ments in medical diagnosis and therapy, we are now able to treat the patient within the
patient - the fetus in utero. Clinicians, researchers and the public have become much
more aware of the lasting impact of fetal life upon the rest of a person's life. As Chool-
ani and Biswas have noted, with the unraveling of developmental origins of health and
disease, we can begin to recognize pivotal trends in the way we address fetal health and
disease. No longer do we accept the limited choices of prenatal diagnosis - to continue
the pregnancy, or not.' Instead, medical pioneers are actively developing means and
methods to treat the fetus in utero. These authors refer to this as the Third Alternative
- the Perinatal Revolution the goal of which is to treat and possibly cure disease in the
prenatal period, and thereby to improve human health across the lifespan.

   *Northwestern University Feinberg School of Medicine, Chicago, IL.
   **US Agency for International Development, Washington, DC.
   -'Charlotte Lozier Institute, Arlington, VA; formerly with the Medical College of Wisconsin and Chil-
dren's Hospital of Wisconsin, Milwaukee, WI.

What Is HeinOnline?

HeinOnline is a subscription-based resource containing thousands of academic and legal journals from inception; complete coverage of government documents such as U.S. Statutes at Large, U.S. Code, Federal Register, Code of Federal Regulations, U.S. Reports, and much more. Documents are image-based, fully searchable PDFs with the authority of print combined with the accessibility of a user-friendly and powerful database. For more information, request a quote or trial for your organization below.

Short-term subscription options include 24 hours, 48 hours, or 1 week to HeinOnline.

Contact us for annual subscription options:

Already a HeinOnline Subscriber?

profiles profiles most