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33 Issues L. & Med. 33 (2018)
Induced Abortion as an Independent Risk Factor for Breast Cancer: A Systematic Review and Meta-Analysis of Studies on South Asian Women

handle is hein.journals/ilmed33 and id is 40 raw text is: 








         Induced Abortion as an

    Independent Risk Factor for

    Breast Cancer: A Systematic

    Review and Meta-analysis of

 Studies on South Asian Women
             Joel Brind, Ph.D.;* StevenJ. Condly, Ph.D.;**
     Angela Lanfranchi, M.D., FACS;*** and Brent Rooney M.Sc.****

ABSTRACT:
Objective: South Asia, a historically low-incidence region for breast cancer,
has produced many recent studies examining reproductive factors. We
compiled these studies to confirm the reality of the significant association
reported in the first, 1996 review of induced abortion as a risk factor, in-
dependent of abortion's known effect in abrogating the protection afforded
by full-term pregnancy.
Methods: We searched the medical literature for English language stud-
ies on breast cancer incidence in women in South Asia published from 1
January, 2000 through 30 June, 2017, using Pubmed, Scholar-Google, and
bibliographic searches. Studies were included which reported overall data
on induced abortion and/or abortion non-specifically. All 20 eligible studies
were of retrospective, case-control design. Data from individual studies were
combined using random effects modeling, following the determination of
significant heterogeneity.


   * Professor of Biology and Endocrinology, Department of Natural Sciences, Baruch College, City Uni-
versity of New York, New York, N.Y.; Ph.D., 1981 Basic Medical Sciences, New York University Graduate
School of Arts and Sciences.
   ** Research Psychologist, Office of Economic Manpower Analysis, United States Military Academy,
West Point, N.Y.; Ph.D., 1999, University of Southern California, Educational Psychology
   -Breast surgical oncologist and Clinical Assistant Professor of Surgery Rutgers Robert Wood Johnson
Medical School, Department of Surgery, Piscataway, New Jersey
   .... Research Director, Reduce Preterm Risk Coalition, Vancouver, Canada. M.Sc., Ohio State Univer-
sity, 19b9.

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