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7 Health Matrix 135 (1997)
How Are Jewish Women Different from All Other Women?: Anthropological Perspectives on Genetic Susceptibility Testing for Breast Cancer

handle is hein.journals/hmax7 and id is 141 raw text is: HOW ARE JEWISH WOMEN DIFFERENT FROM ALL OTHER WOMEN? Anthropological Perspectives on Genetic Susceptibility Testing for Breast Cancer Nancy Press, Ph.D.! Wylie Burke, M.D., Ph.D.t Sharon Durfy, Ph.D. IN 1994, WHEN THE FIRST GENE was found whose mutations predispose some women to breast and ovarian can- cer, researchers stressed that mutations in this BRCA1 gene probably accounted for no more than five percent of all breast cancers' and that these were cancers in women from very high-risk families.2 Yet, the idea of population-based testing is implicit in much of the media coverage of this discovery and has been kept alive by reports that commercial enterprises are gearing up to make testing available in the near future directly to women or through their primary care providers Policy t Medical Anthropologist and Associate Professor in the Department of Psychiatry and Biobehavioral Sciences of U.C.L.A. it Associate Professor and Director in the Women's Health Care Center of the University of Washington. ttt Research Assistant Professor in the Department of Medical History and Ethics of the University of Washington. 1. See Yoshio Miki et al., A Strong Candidate for the Breast and Ovarian Cancer Sus- ceptibility Gene BRCA1, 266 SCIENCE 66, 66 (1994) (explaining the positional cloning methods used to discover the BRCA1 gene). 2. See generally D.F. Easton et al., Genetic Linkage Analysis in Familial Breast and Ovarian Cancer: Results from 214 Families, 52 AM. J. HUM. GENEICS 678, 678 (1993) (analyzing the inherited component of breast and ovarian cancer in a study of families); Kevin Davies, Further Enigmatic Variations, 378 NATURE 762,762 (1995). 3. See generally Natalie Angier, Scientists Identify a Mutant Gene Tied to Hereditary Breast Cancer, N.Y. TIMEs, Sept. 15, 1994, at Al (announcing the discovery of BRCAI gene); Elyse Tanouye, Gene Testing for Cancer to be Widely Available, Raising Thorny Questions,

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