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HRD-80-90 1 (1980-08-14)

handle is hein.gao/gaobabaxc0001 and id is 1 raw text is: AAVVv 11304 3 BY . E COMPTROLLER GENERAL Report To The Congress OF THE UNITED STATES Need For More Effective Regulation Of Direct Additives To Food The Federal Food, Drug, and Cosmetic Act requires that the safety of direct food addi- tives be based on scientific evidence and that the evidence be reviewed and approved by the Food and Drug Administration. However, the act exempts from review and approval sub- stances generally recoqnized as safe by ex- perts or approved for use before 1958 and allows the safety determination for some of those substances to be based on experience drawn from common use in food. The safety of several of these exempted substances, in- cluding saccharin, cyclamate, and nitrite, has been questioned. GAO recommends that the Congress amend the law to eliminate the exemptions and that the Secretary of Health and Human Services publish regulations establishing criteria and guidelines for assessing the safety of additives. Regulations listing substances affirmed as generally recognized as safe should be revised to indicate the kinds of evidence that support their safety. VlHI HIUH ',lrll 113063 HRD-80-90 AUGUST 14, 1980

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