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              Congressional                                             ______
           *   Research Service
               informing the egislative debate since 1914____________________




United States v. McCray and Criminal

Sentences for Fentanyl Analogue Offenses



Updated June 9, 2025

In 2018, the U.S. District Court for the Western District of New York decided United States v. McCray,
rejecting a criminal defendant's challenge to a mandatory minimum sentence for possession with intent to
distribute and distribution of an analogue of fentanyl. McCray has attracted the attention of some
Members  of Congress because it involves a question of statutory interpretation that is relevant to the
regulation of fentanyl analogues.
This Legal Sidebar provides background on the regulation of fentanyl and its analogues under the
Controlled Substances Act (CSA), then summarizes the district court's decision in McCray. The Sidebar
concludes with considerations for Congress related to the McCray decision and the regulation of fentanyl
analogues.

CSA Regulation of Fentanyl and Fentanyl Analogues

The CSA  regulates drugs and other substances-whether medical or recreational, legally or illicitly
distributed-that pose a risk of abuse and dependence. Substances become subject to the CSA through
placement in one of five lists, known as Schedules I through V. Controlled substances in Schedule I are
subject to the most stringent controls, reflecting a finding that a substance has a high potential for abuse
and no currently accepted medical use. Substances in Schedules II through V have accepted medical uses
and have been deemed to pose progressively lower risks of abuse and dependence.
Fentanyl is a Schedule II controlled substance under the CSA, as it has recognized medical uses related to
pain management. Some specific substances chemically related to fentanyl are controlled in Schedule I if
they do not have a currently accepted medical use or in Schedule II if they do. By contrast, cough
medicines containing small amounts of another opiate, codeine, are in Schedule V. (Many other
prescription drugs are not controlled substances subject to the CSA.) In addition, a class of several
thousand fentanyl-related substances (FRS) are temporarily controlled in Schedule I through September
30, 2025. (For additional discussion of the temporary scheduling of FRS, see this Legal Sidebar.)
A substance not specifically designated for control in Schedules I through V may be subject to the CSA as
a controlled substance analogue. Controlled substance analogue is defined in 21 U.S.C. § 802(32) as a
substance not otherwise approved by the Food and Drug Administration or scheduled under the CSA that

                                                                Congressional Research Service
                                                                https://crsreports.congress.gov
                                                                                    LSB11263

CRS Legal Sidebar
Prepared for Members and
Committees of Congress

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