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   , '   Congressional Research Service
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                                                                                                   May 17, 2019

Chronic Wasting Disease (CWD) and Government Response


Chronic wasting disease (CWD) is a degenerative
neurological disorder that affects cervids, including
multiple species of deer, elk, and moose. Infected cervids
may exhibit many symptoms including weight loss or
wasting, poor balance, excessive salivation, difficulty
swallowing, and others. CWD has a 100% mortality rate.
The spread of CWD has impacted both wild and captive
animals, including farm-raised cervids (e.g., for venison
production), across the United States. CWD has caused
economic losses for U.S. farm-raised cervid operations and
may affect wild cervids. As a result, Congress is taking an
active interest in the incidence and management of CWD.

CWD was first discovered in 1967 in Colorado, and since
that time, it has spread across the United States. It may be
transmitted by direct animal-to-animal contact or indirectly
when animals come in contact with infected substances,
such as soil, dust, or forage. According to the U.S.
Geological Survey (USGS), CWD has spread to 26 U.S.
states (as of May 2019; Figure 1) and to Canada, Finland,
Norway, Sweden, and South Korea.

CWD is a type of transmissible spongiform encephalopathy
(TSE) that affects cervids. TSEs, also known as prion
diseases, are a group of degenerative neurological disorders
that result in a spongy appearance of the infected brain.
TSEs are believed to be caused by abnormally folded prion
proteins. Prion proteins are naturally occurring but, when
folded incorrectly, can become both infectious and deadly.
Other TSEs include scrapie, which afflicts sheep and goats,
and bovine spongiform encephalopathy (BSE, also known
as mad cow disease), which affects cattle. TSEs in humans
include Creutzfeldt-Jakob disease.

After infection by CWD, cervids may not exhibit symptoms
for an extended period following exposure. This incubation

Figure I. Distribution of CWD in North America


period can last for a year or longer. No vaccine or treatment
exists for CWD. Two diagnostic post-mortem testing
techniques exist for identifying CWD in cervids.

In some experimental studies, CWD has been shown to
infect mice, squirrels, monkeys, and potentially macaques.
According to the Centers for Disease Control and
Prevention (CDC) in the Department of Health and Human
Services (HHS), there is no strong evidence, to date, of
CWD infecting humans. It is unknown if humans may
become infected by CWD prions, but some research
suggests that CWD may possibly pose a risk to humans. As
a precaution, the CDC and other public health officials
advise caution in handling/processing animals that may be
infected and warn against eating meat from an infected
cervid. The CDC monitors current research on the potential
for CWD transmission to humans and provides
recommendations for hunters to reduce their risk of
exposure.

CWD Management Activities
CWD management activities are shared by several federal
and state departments and agencies. The primary federal
agencies include the Animal and Plant Health Inspection
Service (APHIS) within the U.S. Department of Agriculture
(USDA) and USGS, the U.S. Fish and Wildlife Service
(FWS), and the National Park Service (NPS) within the
Department of the Interior (DOI). Various state agencies-
such as those overseeing agriculture, fish, or wildlife-
often collaborate with federal agencies. Over 25 states have
control programs for both wild and captive cervids.

An early example of state and federal government
cooperation was the CWD Task Force (no longer in
operation). Initiated in 2002 by USDA, DOI, several state
wildlife and agriculture agencies, land grant universities,


                                                                Distribution of Chronic Wasting Diseasee
                                                                         in North America
                                            OWD) rn free~rangin  pula ions
                                                                  Known distbution prior to 2000

                                                    O cwl) in captive taahties
                                                                     (deppulated)
                                                   ....cta CWD in           capre fal udties
                                                   and Ala (t d(current)
                                                     ~based on best avadlable information

Source: CRS, adapted from USGS, National 'Wildlife Health Center, https://www.usgs.gov/centers/nwhc/science/expanding-distribution-
c hron ic-wasting-disease. qt-scien ce ce nter robjects=0#qt-scien ce ce nter robjects.
Notes: Map depicts the distribution area of CWD in North America as of May 2019. This map is regularly updated by the USGS. Both Hawaii
and Alaska (not depicted in the figure) do not have cases of CWD.


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