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                                                                                           Updated August 18, 2015

Algal Toxins in Drinking Water: EPA Health Advisories


On June 17, 2015, the Environmental Protection Agency
(EPA) issued drinking water health advisories for two algal
toxins to help water providers address threats to drinking
water supplies from harmful algal blooms (HABs).

Blue-green algae (cyanobacteria) occur naturally in marine
and fresh water and can produce numerous potent algal
toxins (cyanotoxins). Exposure to cyanotoxins can cause a
range of adverse health effects, from rashes to severe illness
and, rarely, death. A confluence of conditions-including
warm water temperatures, excess nutrients (mainly nitrogen
and phosphorus) and strong sunlight-can trigger explosive
growth of cyanobacteria, creating harmful algal blooms.
These HABs can contaminate drinking water supplied from
surface water or groundwater directly influenced by surface
water. Further, HABs appear to be increasing. EPA's 2009
National Lakes Assessment found microcystins, one of the
more common and potentially harmful cyanotoxins, to be
present in one-third of lakes surveyed nationwide.

In August 2014, microcystins produced by a bloom in Lake
Erie contaminated a water system serving Toledo, Ohio,
and surrounding areas for several days. No federal drinking
water standards were available for managing this or other
cyanotoxins, nor were rapid and sufficiently specific
analytical methods available to meet the needs of water
providers faced with quickly identifying, measuring, and
removing the toxins to ensure the safety of water supplies.
As a trigger for taking action, water managers used the state
guideline of 1 microgram per liter (pg/L) for microcystin-
LR (one of the more common and harmful variants of
microcystin). The immediate problem was resolved;
however, this and other incidents added urgency to EPA's
efforts to assess cyanotoxin risks to public water supplies.

EPA has been conducting research on several common
cyanotoxins-microcystins, cylindrospermopsin, and
anatoxin-a-and evaluating them for possible regulation
under the Safe Drinking Water Act (SDWA). The agency
has also worked to validate analytical methods to enable the
measurement of these cyanotoxins in water at lower
concentrations and with greater accuracy and precision.
However, technical challenges and information gaps on the
toxins' health effects and occurrence have thus far
prevented EPA from determining whether the cyanotoxins
meet the criteria for regulation under the SDWA.

In light of the impacts of the Lake Erie HAB and the
increasing frequency of HABs nationwide, EPA set a goal
to issue health advisories for the three types of cyanotoxins
ahead of the 2015 summertime algal bloom season.


The SDWA authorizes EPA to issue health advisories for
contaminants that are not regulated under the act (42 U.S.C.


§300g- 1 (b)(1)(F)). Health advisories include non-
enforceable guideline values for contaminants in drinking
water (based on non-cancer health effects) and often
include values for different exposure durations: one day, 10
days, several years, and lifetime. Advisories also provide
technical guidance on identifying, measuring, and treating
contaminants in drinking water.

On June 17, 2015, EPA issued several resource documents
related to HABs, including drinking water health advisories
for microcystins and cylindrospermopsin (80 Federal
Register 34637). Because of insufficient health effects data,
EPA was unable to issue an advisory for anatoxin-a.

The advisories include levels for the cyanotoxins in
drinking water at or below which adverse health effects are
not expected to occur based on short-term (10-day)
exposures (Table 1). They also include information on
analytical methods that water providers can use to test for
the presence and concentrations of the toxins and treatment
techniques to remove them from drinking water.

EPA also issued Recommendations for Public Water
Systems to Manage Cyanotoxins in Drinking Water, a
technical document to help water providers develop
cyanotoxin management strategies (e.g., determining when
and how to monitor and treat water and when and how to
notify the public and officials at different toxin levels).

      Table I. Cyanotoxin Health Advisory Levels
        10-day exposures, micrograms per liter (pg/L)

                    Microcystins    Cylindrospermopsin

Children less           0.3                  0.7
than 6 years old
Ages 6 and older         1.6                 3.0
Source: EPA, 2015 Drinking Water Health Advisories for Two
Cyanobacterial Toxins, Fact Sheet, http://water.epa.gov/drinl/
standards/hascience.cfm#micro.
Notes: EPA recommends utilities issue do not drink, do not boil
notices when toxins exceed values for ages 6 and older. Targeted
notification for sensitive groups is suggested when toxin levels exceed
the lower value but not the higher value. EPA worked with Health
Canada to develop health advisories. The World Health Organization
(WHO) issued a provisional drinking water guideline for microcystin-
LR of I pg/L in 1998. Ohio and Oregon use this same guideline level.
Minnesota set a guidance level of 0.04 pg/L. Seventeen countries have
adopted microcystin-LR guidelines ranging from 1.0 pg/L to 1.5 pg/L.



While broadly supporting EPA efforts, the American Water
Works Association has noted technical, policy, and cost
issues with the recommendations document and has asked


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