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    ~Congressional Research Service
    ~~Inforing the legislative debate sirce 1914


                                                                                                  August 8, 2014

Ebola: 2014 Outbreak in West Africa


Overview
An ongoing outbreak of Ebola Virus Disease (EVD), the
largest, most persistent ever documented, and the first in
West Africa, began in March 2014 in Guinea, Sierra Leone,
and Liberia (the affected countries) and has spread to
Nigeria. More people have contracted and died from EVD
in this outbreak than in any single prior outbreak. In the
current outbreak, the case fatality rate (the estimated
percentage of infected persons dying) is about 55%; past
outbreak rates have ranged between 41% and 88%.
Prior human EVD outbreaks had occurred in the
Democratic Republic of Congo, Gabon, Sudan, and
Uganda, primarily in rural and forested areas (Figure 2).
The current outbreak is more geographically extensive and
cases are emerging in both urban and rural settings. Health
experts are accelerating efforts to contain the outbreak, as
transmission in densely populated urban areas may be far
more difficult to control and lead to higher death tolls.
According to the World Health Organization (WHO), from
March through August 6, Ebola was known or suspected to
have infected 1,779 persons and caused 961 deaths; of
these, 1,134 cases had been confirmed in laboratories.


persons face a high risk of infection, as do health care and
funeral workers. Asymptomatic patients are not contagious.
Symptoms. Symptoms typically include fever; weakness;
head, joint, muscle, throat, and stomach aches; and then
vomiting and diarrhea, rashes, and bleeding, often via the
skin and from internal organs. Kidney and liver function
may be impaired; white blood cell and platelet counts may
drop; and shock and death may occur. Early symptoms are
akin to many common illnesses. This may cause some
infected persons not to seek treatment and may increase
rates of EVD transmission. The incubation period (the time
between viral infection and the onset of symptoms) ranges
from 2 to 21 days, and is usually 8 to 10 days.
Treatment. There is no cure for EVD, but EVD treatments
and vaccines are being developed. Treatment focuses on
balancing fluids and electrolytes; maintaining blood
pressure and access to oxygen; and treating attendant
complicating infections. Prompt treatment extends survival
and recovery prospects.

  The current outbreak is bad. It's the biggest most
  complex and the first time it's been present in this region
  of the world. CDC Director, July 31, 2014


Figure I. Global Ebola Outbreaks: 1976-2014


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Source: Created by CRS based on 2014 WHO data.
Ebola Viral Disease
Transmission. Fruit bats are the suspected natural reservoir
of EVD in West Africa, where some people consume bats
and other potentially infected forest animals. Humans can
contract EVD through exposure to bodily fluids of EVD-
infected animals and persons, or through contact with
contaminated surfaces or items (e.g., needles). Inter-human
transmission is the suspected primary source of infection in
West Africa. During outbreaks, close associates of infected


      Prevention. In clinical settings, suspected EVD cases are
IW% isolated, and health workers wear personal protective
      equipment (PPE) and sterilize and avoid contact with
      contaminated objects, but some health centers in the
Saffected are unable to undertake such responses. Lack of
70%   knowledge of EVD in the region has hindered efforts to
      avert person-to-person transmission (see below), but public
Mf education campaigns focusing on EVD prevention and non-
   stigmatization of known or suspected EVD patients are
     under way. Health workers are working with community
Sleaders to develop alternatives to cultural practices (e.g.,
      funeral rites and visiting the ill) that might spread EVD.


Responses
International Response. The WHO, which on August 8
declared EVD a Public Health Emergency of International
Concern, is coordinating the international response to the
outbreak. Through its Global Alert and Response Network
(GOARN), WHO is coordinating with the U.S. Centers for
Disease Control and Prevention (CDC), the U.S. Agency
for International Development (USAID), United Nations
agencies, and others to support affected countries'
responses. On July 31, WHO announced that it was
launching a $100 million Ebola response plan, which will
channel resources through the newly established Ebola
Outbreak Coordination Center, in Conakry, Guinea. On
August 4, 2014, the World Bank Group pledged up to $200
million in emergency funding to help the affected countries
contain EVD. Such international support is critical; the


www.crs.gov 1 7-5700


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