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85 Z. Rechtsmedizin 1 (1980)

handle is hein.journals/injlegame85 and id is 1 raw text is: Zeitschrift fur Z Rechtsmed 85, 1-4 (1980) Rechtsmedizin © Springer-Verlag 1980 Originalarbeiten / Original Works Results on Forensic Application of the C3 System* G. Geserick, O. Prokop, and H. Waltz Institut fur gerichtliche Medizin der Humboldt-Universitat zu Berlin, Hannoversche Strate 6, DDR-104 Berlin Summary. The results of the application of the C3 system to 155 cases of disputed paternity are presented. In this preselected material (none of the 234 accused men could be excluded by any of the usual markers of red blood cells and serum) 23 men were excluded. Of these 23 exclusions, 17 could be examined in the HLA-system and were confirmed by this system. In 211 mother-child pairs no theoretically impossible combinations were observed. Key words: Blood groups, C3 system - Complement Zusammenfassung. Das C3-System wurde bei 155 Fallen strittiger Vaterschaft eingesetzt. Es handelte sich um ein ausgelesenes Untersuchungsgut, da in allen Fallen die 234 beschuldigten Manner durch den Einsatz der iblichen gene- tischen Erythrozyten- und Serummerkmale nicht auszuschlieBen waren. 17 der 23 ausgeschlossenen Probanden konnten im HLA-System untersucht werden, wobei alle Ausschlhsse bestatigt wurden. Die C3-Typisierung von 211 Mutter-Kind-Paaren erbrachte keine Abweichungen von der Erbregel. Schlisselworter: Blutgruppen, C3-System - Komplement Since the discovery of the C3 polymorphism in man [1-4] it has been intensively studied from two points of view: population genetics and forensic application. The numerous studies of the frequency in different populations and of the in- heritance were summarized by Rittner and Rittner [5], and by Geserick [6]. The results of C3 typing in our population (n = 1326; allele frequency: C3F = 0.1836, C35 = 0.8130, C3a = 0.0034) and of family studies have been given elsewhere [7]. In addition, we have previously reported on 240 families typed with the Pt tech- * Vortrag auf dem ,,III. Workshop on the Genetics of the Complement System in Koin, Mai 1979 Offprint requests to: Dr. G. Geserick (address see above) 0044-3433/80/0085/0001/$ 1.00

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