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103 Z. Rechtsmedizin 1 (1989-1990)

handle is hein.journals/injlegame103 and id is 1 raw text is: Zeitschrift fur Z Rechtsmed (1989) 103:1-20 Rechtsmedizin © Springer-Verlag 1989 Original works Komplikationen nach Zelltherapie* ** J. Bohl1, H.H. Goebelh, L. Potsch2, W. Esinger3, G. Walther2, R. Mattern2 und K. H. Merkel4 1Abteilung fur Neuropathologie, Pathologisches Institut der Johannes-Gutenberg-Universitat Mainz, D-6500 Mainz, Bundesrepublik Deutschland 2Institut fur Rechtsmedizin der Johannes-Gutenberg-Universitat Mainz, D-6500 Mainz, Bundesrepublik Deutschland 3Pathologisches Institut der Stadtischen Krankenanstalten Ludwigshafen, D-6700 Ludwigshafen, Bundesrepublik Deutschland 4Pathologisches Institut, Krankenhaus Am Urban, Berlin, D-1000 Berlin, Bundesrepublik Deutschland Complications following cell therapy Summary. So far, the law in the Federal Republic of Germany still allows the injection of fresh-cell preparations from animals as a roborant to increase the vitality of the organism and to strengthen the body's immune defense system. The use of ,,sicca-cell preparations was provisionally forbidden in 1987 by the Federal Health Organization (Bundesgesundheitsamt; BGA). Prohibition of fresh-cell injections would have exceeded the authority of this office, although the same serious reservations also applied in the case of this treatment method. Several publications that have appeared since 1955 have reported serious complications of this therapy, some life-threatening and some even lethal. Two further cases are now added: (1) A woman aged 69 had been receiving treatment with cell injections for 9 years. Immediately after an injection of sicca cells she collapsed and was hospitalized; 7 days thereafter she developed an ascending paralysis with increasing inability to swallow or breathe. She died 25 days after the injection as a consequence of central and peripheral respiratory failure. Autopsy revealed the alterations typical for acute Landry-Guillain-Barre-Strohl syndrome. (2) A 76-year-old healthy woman had been receiving treatment with fresh-cell preparations for several years. After an injection of cell suspensions a painful local swelling was observed. The symptoms were interpreted as the consequence of an iatrogenic local hematoma, and repeated punctures were performed to ob- tain blood. The patient was transferred to a surgical department for further * Gewidmet Herrn Professor Dr. Adebahr zu seinem 65. Geburtstag (1989) ** Nach einem Vortrag, gehalten auf der 67. Jahrestagung der Deutschen Gesellschaft fur Rechtsmedizin in Kloster Banz (8623 Staffelstein) 20.-24. September 1988 (Lit. Verz. Nr. 6) Sonderdruckanfrage an: J. Bohl

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