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GAO-07-294R 1 (2007-01-31)

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        Accountability * Integrity * Reliability
United States Government Accountability Office
Washington, DC 20548


          January 31, 2007

          The Honorable Tom Coburn, M.D.
          Ranking Minority Member
          Subcommittee on Federal Financial Management,
          Government Information, and International Security
          Committee on Homeland Security and Governmental Affairs
          United States Senate

          Subject: National Institutes of Health Extramural Research Grants:
                  Oversight of Cost Reimbursements to Universities

          Dear Senator Coburn:

          The Department of Health and Human Services' (HHS) National Institutes of Health (NIH) is
          the nation's leader in conducting and sponsoring biomedical research. More than 80 percent
          of NIH's budget, which totaled over $28 billion in fiscal year 2006, is used to support
          extramural research, which is primarily conducted at over 500 universities' nationwide. NIH
          reimburses universities for direct costs that can be specifically attributed to research
          sponsored by NIH grants, including costs for labor and materials used solely to carry out the
          research. It also reimburses universities for indirect costs, which include various facility and
          administrative expenses incurred by the universities for the shared support of such research.

          To be reimbursed for direct and indirect costs, universities must properly identify and claim
          them in accordance with federal guidance. Office of Management and Budget (OMB) Circular
          No. A-212 establishes the principles for determining the types of direct and indirect costs that
          are allowed to be claimed and the methods for allocating such costs to federally funded
          research. Because indirect costs cannot be specifically attributed to a particular research
          grant, they are charged via an indirect cost rate that is applied to the direct costs for each
          grant agreement. Each university develops a proposed indirect cost rate, based on
          information such as the amount of physical space used for conducting research. A
          university's final indirect cost rate is generally determined by negotiating its proposed rate
          with HHS's Division of Cost Allocation (DCA).3 DCA is responsible for ensuring that the final
          negotiated indirect cost rate complies with OMB Circular No. A-21. Additionally, for each
          university that received $25 million or more in federal funds for its most recently completed


          'We are using the term university to refer to any domestic institution of higher education.
          22 C.F.R. pt. 220 (2006).

          3OMB assigns responsibility for negotiating indirect cost rates to HHS's DCA or the Department of
          Defense's Office of Naval Research, normally depending on which department provided more funds to
          the educational institution over the past 3 years. According to DCA, its staff negotiates rates for more
          than 90 percent of the universities that receive NIH grants.


GAO-07-294R Extramural Research Grants

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