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HRD-80-70 1 (1980-03-28)

handle is hein.gao/gaobabamp0001 and id is 1 raw text is: -RELEASED RESTRCTED .-Not to be released outside the General Acco ttg Offe except on the asis of specif 8approyi GAO by the Offic, of Congressionl -jati. United States General Accounting Office Human Resources Washington, DC 20548 Division B-198010 MARCH 28, 1980 The Honorable Charles Pashayan, Jr. House of Representatives Dear Mr. Pashayan: 112170 Subject: LAlternatives to Use of Animals in Research (HRD-80-70) In response to your March 26, 1979, letter and subsequent discussions with your office, we have inquired into the con- cerns you expressed regarding alternatives to the use of live animals in research and testing. Your letter identified several areas of concern, including promotion of existing alternatives, development of additional alternatives, train- ing of researchers in alternative methods, unnecessary dupli- cation of animal tests, and steps that could be taken to prevent unnecessary cruelty to animals. As discussed with your office, we found little informa- tion available to enable us to adequately respond to your concerns without extensive audit work. It was therefore agreed that we would provide information on the actions the National Institutes of Health (NIH) has taken, or plans to take, to better control the use of animals in research, and to assure that alternative methods are used when appropriate. We have discussed these issues with several NIH offi- cials and with representatives of various private organiza- tions concerned with biomedical research and animal welfare. Also, we have reviewed literature on this subject that was recommended by several persons we interviewed. BACKGROUND The term alternatives, when applied to the use of animals in biomedical research, is generally recognized as covering one or more of the following possibilities: --Not using any laboratory animals. --Reducing the number of animals required. --Refining existing methods to minimize the amount of animal suffering and stress. (103962)

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