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HRD-79-51 1 (1979-03-30)

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              RESTRCTED - Not to be released outsdo the General (0106
              Accountirr Cff o exccpt on the basis of specific approval
   +1by the Office of Congressioal' 'Relatime i
                   UNITED STATES GENERAL ACCOUNTING OFFICE
                          WASHINGTON, D.C. 20548 RELEASED

HUMAN ASOURCXS
   DIVISION                                       MARCH 30, 1979
       B-164031(2)

       The Honorable Henry A. Waxman
       House of Representatives

       Dear Mr. Waxman:

             In your May 2, 1977, letter you asked us to review
       certain aspects of the National Cancer Institute's (NCI's)
       carcinogenesis program. In our July 26, 1978, report to
       you (HRD-78-143) we provided information on

             --the roles and responsibilities of advisory groups
               to the carcinogenesis program and factual data on
               the relationships among advisory group members and
               organizations that could be affected by NCI
               activities,

             --the extent that advisory groups encouraged or
               discouraged NCI efforts to conduct and sponsor
               research in cancer prevention and identification
               of environmental carcinogens, and

             --the effect of the Clearinghouse on Environmental
               Carcinogens on the program.

             At that time we said that we would provide information
        to you on the remaining questions you had asked on program
        operations. This report addresses your concerns about

             --funding and staff allotments,

             --the extent and causes of the backlog in the review
               and completion of bioassay reports,

             --the efficiency of and need for improvements in
               contract management activities and the adequacy of
               quality contrbls over bioassay work,    ,

             --the structure of the program and the emphasis on
               environmental carcinogens, and

                                                          H RD -79-51
   lllllll OH
                           5-0 V&                          (10387)
       109166

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