HeinOnline is a subscription-based resource containing thousands of academic and legal journals from inception; complete coverage of government documents such as U.S. Statutes at Large, U.S. Code, Federal Register, Code of Federal Regulations, U.S. Reports, and much more. Documents are image-based, fully searchable PDFs with the authority of print combined with the accessibility of a user-friendly and powerful database. For more information, request a quote or trial for your organization below.
![handle is hein.gao/gaobaacjh0001 and id is 1 raw text is:
DOCUMENT RESUME ,2/ ,2
02513 - [A1852875] (*&ZtV1ite4-
Need to Establish Safety and Effectieness of Antibiotics Used
in Animal Feeds. HRD-77-81; B-164031(2). June 27, 1977. 47 pp. +
2 appendices (5 pp.).
Report to Rep. John Z. Ross, chairman, House Committee on
Interstate and Foreign Commerce: oversight and Investigations
Subcommittee; by Elmer B. Staats, Comptroller General.
Issue Area: Consumer and Worker Protection: Identifying Needs
for Standards and Regulations (901); Food (1700) ;Consumer
and Worker Protection: Standards, Laws, and Regulations
Enforcement (903).
Contact: Human Resources Div.
Budget Function: Health: Prevention and Control of Health
Problems (553); Agriculture (350).
Organization Concerned: Dpartment of Health, Education, and
Welfare; Food and Drug Administration.
Congressional Relevance: House Committee on Interstate and
Foreign Commerce: oversight and Investigations Snbcommittee.
Authority: Federal Food, Drug, and Cosmetic Act, as amended (21
U.S.C. 301 et seq.). Food Additive Amendments of 1958 (P.L.
85-929). Drug Amendments of 1962 (P.L. 89--781). 21 U.S.C.
360 et seq. 21 C.F.R. 514.1 et seq.
The Food and Drug Administration (FDA) has permitted
the continued use of low levels of several antibiotics in animal
feeds. Findings/Conclusions: The Sdfety and effectiveness of
the continued use in animal feeds of several antibiotics,
particularly penicillin, tatraclclines, and sulfaquinoxaline,
has not been established. The possibility ekists that
antibiotic-resistant bacteria may develop, and that this
resistance may be transferred from animal to man. on April 15,
1977 the FDA decided to restrict the use of these drugs in
animal feeds. Questions are raised concerning the use of the
Rational AdvLsory Food and Drug Committee by the FDA, including
insufficient expertise, conflict of interest, and improper
involvement in regulatory matters instead of policy only.
Recommendations: FDA shodld determine the safety and
effectiveness of antibiotics used in animal feeds based on
available data,and withdraw approval of any not shown to be safe
and effective. Policy advisory committees should be used only to
review brot-1 policy questions in accordance with FDA
regulations, and their members made aware of their
responsibilities with regard to and the restrictions of
conflict-of-interest laws and regulations. (Author/DJ?,)](ViewImageLocal?handle=hein.gao/gaobaacjh0001&div=1&collection=&method=preview&ext=.png&size=3)