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92 Z. Rechtsmedizin 1 (1984)

handle is hein.journals/injlegame92 and id is 1 raw text is: Zeitschrift fSr Z Rechtsmed (1984) 92 :i-25 Rechtsmedizin © Springer-Verlag 1984 Ubersichtsreferat / Review Article Iatrogene histopathologische Befunde Eine systematische Zusainmenstelrng R. Vock Institut fur Rechtsmedizin der Universitat Wiirzburg, Versbacher Str. 3, D-78&O Warzburg, Bundesrepublik Deutscbland Iatrogenic Histopathological Findings: A Systematic Compilation Sunnmary. A series of drugs and diagnostic agents are deposited (mostly in a metabolized form) in various human organs or cause characteristic histologi- cal pictures there. These iatrogenic alterations can frequently be recognized even after a short time and can be demonstrated for varying lengths of time. They may become relevant in various respects in terms of forensic medicine: (1) as an aid to identification in unknown cadavers or cadaver parts, (2) in establishing iatrogenic damage, (3) as an evaluation of findings in sudden and unexpected death from natural causes, and (4) in problems of insurance law with regard to morphological demonstration of chronic drug abuse, especially abuse of analgesics. In a systematic review broken down according to organs, a series of these drugs or diagnostic agents are presented with the morphological alterations they caused, the methods of histological demonstration and the duration of identifiability. Key words: Iatrogenic histological organ changes - Aid to identification in unknown cadavers and cadaver parts - Iatrogenic damage - Sudden and unex- pected death from natural causes - Morphological demonstration in chronic drug abuse Zusanunenfassung. Eine Reihe von Medikamenten and Diagnostika lagert sich meist in metabolisierter Form. in den verschiedenen menschlichen Orga- nen ab oder verursacht dort charakteristische histologische Bilder. Diese iatrogenen Verinderungen sind haufig schon nach kurzer Zeit zu erkennen and lassen sich unterschiedlich lange nachweisen. Sie kannen unter ver- schiedenen Aspekten rechtsmedizinische Relevanz erlangen: () als Identifi- kationshilfe bei unbekannten Leichen bzw. Leichenteilen, (2) bei der Frage der iatrogenen Schidigung, (3) als Blefundbewertung beim plbtzlichen und

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