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65 Dtsch. Z. Ges. Gerichtl. Med. 1 (1969)

handle is hein.journals/injlegame65 and id is 1 raw text is: Dtsch. Z. ges. gerichtl. Med. 65. 1-7 (1969) Histochemical Changes at Base Level of Umbilical Cord I. Behaviour of Alkaline and Acid Phosphatases G. Lo MENZO Institute of Forensic Medicine and Insurance University of Catania (Head: Prof. F. NICoLETTI) Received 14. August 1968 This subject has already drawn many authors' interest, particularly with regard to macroscopical and histological changes of umbilical cord. The problem is particularly important when we are in the impos- sibility of surveying the lungs (for example if they have been lost), and it is extremely important to ascertain whether extrauterine life has been lived. In 1898 KOCKEL reported that a leucocyte infiltrate in the subcutaneous tissue of periumbilical region should be considered as a characteristic of newborn that lived an extrauterine life. But such an interpretation was, however, restricted by later studies of GLINSKY and HORoSZKIEwICZ (1903) who gave no importance to a superficial infiltrate, except when it, in a notable quantity, marked the boundaries of the funiculus base: that generally is found to be present after about 24 hours of extrauterine life. GRXFF (1922) thought that not even this evidence should be taken into account. Afterwards, GIORDANo (1932) and MANUZA (1935), confirmed the studies of GLINSKY and HOROSZKIEwIcZ, pointing out that both a leucocyte slight infiltrate and its absence could not mean that newborn had or had not lived an extrauterine life. Only a remarkable infiltrate at the funiculus base should be considered as a sign of extrauterine life, prolonged as long as the second or third day. Subsequently, CAMBA confirmed the data reported by MANUNZA, by VEIGA BE CARvALIO and FITTIPALDI about the finding of plasmacells in the perifunicular infiltrate of hereditary luetic newborn. Reading once again previous literature about this subject, we con- sidered that a more detailed histochemical study of the skin surrounding the umbilical cord base could be interesting, since sure changes occur after birth and go on as long as funiculus falls. Material and Methods The investigation was carried out on 16 either male or female newborn observed in our section. Among these, 5 lived no extrauterine life (one of these 5 was a fetus in the 6th month); among the remaining 11, two lived 72 hours, one 48 hours, one 24 hours, 1 Dtsch. Z. ges. gerichtl. Med., Bd. 65

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